2
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10552 | Bitopertin (R enantiomer) | RO4917838 (R enantiomer),RG1678 (R enantiomer),Bitopertin R enantiomer | GlyT |
Bitopertin R enantiomer (RG1678 R enantiomer) is the R-enantiomer of Bitopertin. Bitopertin is a noncompetitive glycine reuptake inhibitor and inhibits glycine uptake at human GlyT1 (IC50: 25 nM). | |||
T6788 | Bitopertin | Paliflutine,RO4917838,RG1678 | GlyT |
Bitopertin (Paliflutine) (RG1678, RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM in Chinese hamster ovary cells. |